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Thanks for your reply. Grace has been on these same tablets since she was diagnosed at birth. She regularly sees a peadiatrician on the Gold Coast who has an interest in Endocronology, but she is also under the guidance of Mike Thomsett, an Endocronologist in Brisbane. She hasn't really had any problems with her medication, she has had one crisis and a couple of bouts of vomitting which has required hospitalisation. She is a little on the short side - about the 30th percentile, and about the 50th percentile for weight.